The Ireland coaching group have named the match day 23 that will take on Italy at Soldier Field in Chicago on Saturday,
Both Will Addison and Ross Byrne will likely earn their first Ireland caps off the bench.
Rhys Ruddock captains the youthful side, and is joined in the back row by Leinster teammates Josh van der Flier and number 8, Jack Conan.
Quinn Roux partners Tadhg Beirne in the second row, while hooker Niall Scannell is joined in the front row by Leinster props Jack McGrath and Andrew Porter.
Jordan Larmour starts at full-back, with Andrew Conway and Jacob Stockdale manning the wings.
Garry Ringrose partners Bundee Aki in the centre.
And in the absence of both Conor Murray and Jonathan Sexton, Luke McGrath and Joey Carbery form the three-quarters.
Ireland are back at the scene of their historic victory over the All Blacks two years ago, and Joey Carbery is delighted to return to the Windy City.
The Rugby Weekend fixture against Italy will be broadcast by Eir.
Here's your Ireland team for #IREvITA @TheRugbyWeekend in Soldier Field.#shouldertoshoulder pic.twitter.com/7mWEJVGqeS
— Irish Rugby (@IrishRugby) November 1, 2018
Digital Desk