Officials are calling for a "special effort" from donors to restore blood supplies around the country.
The Irish Blood Transfusion Service says the national supply is now down to just three days.
It wants an extra 1,500 donations over the next three weeks to stabilise levels, particularly from 'O positive' and 'O negative' donors.
The drive aims to return to a seven-day supply.
According to the service, just 3% of those eligible, donate blood.
On the opposite side of the spectrum, 25% of us will require a blood transfusion at some point in our lives.
For those willing to donate, a clinic will be in operation today in Wexford town and again throughout Sunday.