Twitter has begun cutting jobs in the wake of Elon Musk's takeover.
It's letting go around half of it's global workforce, including some of the 500 staff in Ireland.
Workers have been locked out of their offices for the day.
The move by tech companies to cut staff is a worry for the sector in Ireland, according to an economist.
It follows the news of job losses at Stripe which was founded by Tipperary brothers John and Patrick Collison
DCU Professor Edgar Morganroth says it's worrying if the trend in the tech sector continues.
"The tech sector is clearly very important to the Irish economy
"We have very highly paid staff in these firms and they obviously are spending their money in the wider economy.
"If we see significant job losses in this sector, it is likely to have an impact on the wide economy."
Tech companies may have expanded too quickly in the past year or two, according to the Tanaiste.
Leo Varadkar was reacting to the jobs losses at Twitter and Stripe announced in the last couple of days.
All Twitter staff were due to receive an email telling them whether they had a job or not in the last hour.
New owner Elon Musk is expected to reduce the platform's 8-thousand strong workforce by as much as half.
Speaking to CNBC from Singapore Tanaiste Leo Varadkar says there are still opportunities in the sector.
"My first thoughts are with the people who are going to get bad news today, whether it's people working in Stripe or people working in Twitter and other companies who are going to find out that they are going to lose their jobs.
"Tech companies expanded very quickly, they probably expanded a little bit too quickly and as a result of that they have to lay off some staff.
"But the number of vacancies in the sector still out weighs the number of people looking for employment."
It's unclear how many Irish staff will lose their jobs, with Twitter aiming to inform everyone by 4 o clock Irish Time.
