There has been a 244% increase in measles cases in Ireland between 2017 and 2018.
According to UNICEF Ireland, there were 86 cases here last year, up from 25 on the previous year.
The charity is warning that global cases are also surging, with 98 countries reporting a rise.
UNICEF Ireland Executive Director Peter Power says it is a worrying trend considering there is a vaccine available.
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"It really is a wake-up call," he said.
"We have a safe, effective and inexpensive vaccine which has saved a million lives every year for the last 20 years.
"There really is no excuse now for the misinformation, the mistrust and the complacency that has crept into measles vaccination around the world."
